Extreme Bendability of DNA Less than 100 Base Pairs Long Revealed by Single-Molecule Cyclization
نویسندگان
چکیده
منابع مشابه
Extreme bendability of DNA double helix due to bending asymmetry.
Experimental data of the DNA cyclization (J-factor) at short length scales exceed the theoretical expectation based on the wormlike chain (WLC) model by several orders of magnitude. Here, we propose that asymmetric bending rigidity of the double helix in the groove direction can be responsible for extreme bendability of DNA at short length scales and it also facilitates DNA loop formation at th...
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ژورنال
عنوان ژورنال: Science
سال: 2012
ISSN: 0036-8075,1095-9203
DOI: 10.1126/science.1224139